Hidden suppressive interactions are common in higher-order drug combinations
نویسندگان
چکیده
منابع مشابه
Suppressive drug interactions between antifungals.
In this issue of Chemistry & Biology, Cokol and colleagues report a systematic study of drug interactions between antifungal compounds. Suppressive drug interactions occur more frequently than previously realized and come in different flavors with interesting implications.
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BACKGROUND Drug-drug interactions (DDIs) comprise an important problem in medical oncology practice. We systematically reviewed the frequency of DDIs in oncology. METHODS We searched PubMed for eligible articles and on-line databases for abstracts of major oncology meetings. RESULTS Eight studies reported on the frequency of DDIs: six evaluated the frequency of potential DDIs, while two stu...
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ژورنال
عنوان ژورنال: iScience
سال: 2021
ISSN: 2589-0042
DOI: 10.1016/j.isci.2021.102355